Segura Segura Rodrigo Andrés

Email: 
rodrigo.segura@usach.cl
Teléfono: 
27 181 172

Abstract

Optimization of methodology of stripping voltammetry for the determination of trace metals in environmental samples

Línea(s) de investigación: 
Química analítica, Análisis instrumental, Electroanálisis.
Jerarquía: 
Asociado
Grados académicos /educación: 
Químico, Pontificia Universidad Católica de Chile 1998
Doctor en ciencias exactas mención química, Pontificia Universidad Católica de Chile. 2005
Laboratorio de Aguas. Ingeniería Hidráulica y Ambiental. Facultad de Ingeniería. Pontificia Universidad Católica de Chile (2005)
Laboratorio de Química Analítica. Departamento de Química Universidad de Chile. Posdoctorado FONDECYT (2006-2007)
Publicaciones: 
  1. I.Crivelli, B. Loeb,* R. Segura, C. Andrades, M.A. Francois. (2000), Experimental evidence of the disproportionation equilibrium in copper mixed valence complexes. Polyhedron. 19: 2289-2295. IF=2.057
  1. V. Arancibia, R. Segura, J.C. Leiva, R. Contreras, M. Valderrama. (2000),. Supercritical Fluid Extraction-Gas Chromatography or SFE-Electroanalysis of Metal Chelates from Different Sample Matrices. J. Chromatogr. Sci. 38: 21-26.  IF=0.884
  1. V. Arancibia, M. Valderrama, P. Rodríguez, F. Hurtado, R. Segura. (2003), Quantitative extraction of sulfonamides in meats by supercritical methanol-modified carbon dioxide: A foray into real-world sampling. J. Sep. Sci. 26: 1710-1716. IF=2.733
  1. Arancibia V*, Valderrama M, Madariaga A, Zúñiga M C, Segura R,(2003). Extraction of nitrofurantoin and its toxic metabolite from urine by supercritical fluids. Quantitation by high performance liquid chromatography with UV detection. Talanta. 6: 377-383. IF= 3.794
  1. Arancibia V*, Alarcón L, Segura R, (2004). Supercritical fluid extraction of cadmium as Cd-oxine complex from human hair Determination by square wave anodic or adsorptive stripping voltammetry. Anal. Chim. Acta 50: 189-194 4.  IF= 4.555
  1. Arancibia V*, Valderrama M, López  A, Segura R, Zuñiga M C, (2006). Extraction of arsenic as diethyl dithiophosphate complex with supercritical fluid and quantitation by cathodic stripping voltammetry. Talanta 68: 1567-1573 IF= 3.794.
  1. Segura R*, Arancibia V, Zúñiga M C, (2006). Sequential extraction of Cu, Zn, Pb and Cd in contaminated sediments from the Mapocho River (Chile). J Geochem Explor. 91: 71-80, IF= 1.440
  1. Peña C, Arancibia V*, Segura R, (2006). Evaluation of powdered infant formula milk as chelating agents for copper under gastric conditions of a stimulated baby stomach. Analyt. Sci. 22: 1197-1200.  IF= 1.255
  1. Segura R*, Toral M I, Arancibia V. (2008) Determination of Fe (III) by Adsorptive Stripping Voltammetric with 1-(2-pyridylazo)-2- naphthol using a Bismuth Films electrode. Talanta 75: 973-977. IF= 3.794.
  1. Arancibia V*, Zuñiga M, Segura R, Esteban M, Zuñiga M C.(2010). Optimization of experimental parameters in the determination of Zinc in sea water by adsorptive stripping voltammetry. J Brazil Chem Soc 21: 255-261.  IF= 1.434
  1. Segura R*, Pradena M, Pinto D, Godoy F, Arancibia V, Nagles E.(2011)   Adsorptive Stripping Voltammetry of Nickel with 1-nitroso-2-napthol using a Bismuth Film electrode. Talanta 85: 2316-2319. IF= 3.794.
  1. Mattos I L*; Padilla  F; Zagal J H; Falcao  E; Segura R.(2011). Screen-printed electrode modified with silver hexacyanoferrate-nafion (r) for ascorbic acid determination.  J Chil Chem Soc. 56: 803-807. IF= 0.448
  1. Nagles E; Arancibia V*; Rojas C; Segura R. (2012). Nafion-mercury coated film electrode for the adsorptive stripping voltammetric determination of lead and cadmium in the presence of pyrogallol red. Talanta 99: 119-124.  IF= 3.794.
  1. Leiva M.*, Morales S, Segura R.(2013) Comparative Measurements 1 and their Compliance with Standards of 2 Total Mercury Analysis in Soil by Cold Vapour and Thermal 3 Decomposition, Amalgamation, and Atomic Absorption Spectrometry. Water Air Soil Poll 56: 803-807. IF= 1.625.
  1. Tapia Y*, Diaz O, Pizarro C, Segura R, Vines M, Zúñiga G, Moreno-Jiménez E. (2013). Atriplex atacamensis and Atriplex halimus resist As contamination in Pre-Andean soils (northern Chile). Sci Total Environ 450-451: 188-196. IF= 3.286
  2. Rodrigo Segura, Jorge Vélez, Fernando Godoy, María P. Oyarzun, Pamela Sepúlveda (2013) Determination of cadmium and lead by anodic Stripping Voltammetry with glassy carbon electrode modified with polymeric meso-tetrakis tetrabromo thenyl porphyrin. (TBrTP). International Journal of Electrochemical Science 10: 12005-12014. IF=2,808
  3. Fernando Godoy, Alejandra Gómez, Rodrigo Segura, Fabio Doctorovich, Juan Pellegrino, Carina Gaviglio, Paulina Guerrero, A. Hugo Klahn , Mauricio Fuentealba, María Teresa Garland. Synthesis, structure, and reactivity of (h5:h1-C5Me4(CH2)2NMe2) Re(CO)2. Electron transfer behavior of a nitrosyl derivative. Journal of Organometallic Chemistry 765:8-6.  IF= 2,336 https://doi.org/10.1016/j.jorganchem.2014.04.019
  4. Fernando Godoy, ,Alejandra Gómez, Nicolas Agurto, Michelle Muñoz, Rodrigo Segura, Carlos P. Silva, Jorge Pavez, José H. Zagal, A. Hugo Klahn, M. Fuentealba, Andres Ibañez, Maria Teresa Garland (2015). Synthesis, reactivity, electrochemical behaviour, and molecular structure of crown ether cyrhetrene complexes. Journal of Organometallic Chemistry 788: 2-48.  IF=2,304   https://doi.org/10.1016/j.jorganchem.2015.04.031
  5. Rodrigo Segura, Jaime Pizarro, Eduardo Pino, Karina Diaz Alan Placencio Fernando Godoy and Francisco Recio (2015). Development of electrochemical sensors for the determination of selenium using electrodes modified with gold nanoparticles (AuNPs) 220: 2663-269.  Sensors & Actuators: B. Chemical IF=7,100

  6. Karina Vázquez, Christian Espinosa-Bustos, Jorge Soto-Delgado, Ricardo A. Tapia , Javier Varela , Estefanía Birriel , Rodrigo Segura, Jaime Pizarro, Hugo Cerecetto, Mercedes González , Margot Paulino and Cristian O. Salas (2015) New aryloxy-quinone derivatives as potential Anti-Chagasic agents: Synthesis, trypanosomicidal activity,lectrochemical properties, pharmacophore elucidation and 3D-QSAR analysis  220: 263-269 RSC Advances IF=3,119 https://doi.org/10.1039/C5RA10122K

  7. Rodrigo A. Segura, Jaime A. Pizarro, María P. Oyarzun, Alejandra Castillo, Alan Placencio. (2019).Determination of lead and cadmium in water samples by adsorptive stripping voltammetry using a bismuth film/1-Nitroso-2-Napthol/Nafion modified glassy carbon electrode.  11: 1707-1719 International Journal of Electrochemical Science IF=1,573 http://electrochemsci.org/papers/vol11/110201707.pdf

  8. Oscar P. Díaz, Yasna Tapia, Rubén Pastene3, Marcia Cazanga, Rodrigo Segura, Santiago Peredo. (2016). Lupinus microcarpus Growing in Arsenic—Agricultural Soils from Chile: Toxic Effects and It Potential Use as Phytoremediator Plant.  7:116-128 Journal of Environmental Protection IF=0,600
  9. Erick Flores, Jaime Pizarro, Fernando Godoy, Rodrigo Segura, Alejandra Gómez, Nicolás Agurto, Pamela Sepúlveda. (2017). An electrochemical sensor for the determination of Cu(II) using a modified electrode with ferrocenyl crown ether compound by square wave anodic stripping voltammetry  251:433-439 Sensors & Actuators: B. Chemical IF=7,100 https://doi.org/10.1016/j.snb.2017.05.058

  10. Margarita Montoya, Jaime A Valderrama, Rodrigo Segura, Judith Faundes, Sophia Mejías, J. Andrea Ibacache. (2017). Synthesis and Antiproliferative Evaluation of New Aminoisoquinolinequinones Derived from p-Phenylenediamine, Benzidine and Dapsone. 9:127-134 Journal of Chemical and Pharmaceutical Research 

  11. Rodrigo Segura, Karina Díaz, Jaime Pizarro, Alan Placencio, Diego Tapia and Ángelo Fajardo. 62, Nº 4 (2017) 3661. Anodic Stripping Voltammetric Determination of Lead using a Chemically Modified Electrode based on Aza Crown Ether. Journal of the Chilean Chemical Society. IF= 0,617 (2019)
  12. Jaime Pizarro, Erick Flores, Victor Jimenez, Tamara Maldonado, Claudio Saitz Andres Vega, Fernand Godoy, Rodrigo Segura. (2019). Synthesis and characterization of the first cyrhetrenyl-appended calix[4]arene macrocycle and its application as an electrochemical sensor for the determination of Cu(II) in bivalve molluscs using square wave anodic stripping voltammetry. 281:115-122 Sensors & Actuators: B. Chemical. IF=7,100 https://doi.org/10.1016/j.snb.2018.09.099

  13. Rodrigo Segura, Angelo Fajardo, Jaime Pizarro, Diego Tapia, Pablo Jara. (2019). Determination of norepinephrine using a glassy carbon electrode modified with graphene quantum dots and gold nanoparticles by square wave stripping voltammetry.  (2019).  49:423–432 Journal of Applied Electrochemistry IF=2,384 https://doi.org/10.1007/s10800-019-01288-0

  14.  Jaime Pizarro, Rodrigo Segura, Diego Tapia, Soledad Bollo, Paulina Sierra‐Rosales. (2019) Electroanalytical determination of Cd(II) and Pb(II) in bivalve mollusks using electrochemically reduced graphene oxide-based electrode 31:   Electroanalysis IF= 2,544 https://doi.org/10.1002/elan.201900061
  15. Christian Espinosa‐Bustos, Karina Vázquez, Javier Varela, Hugo Cerecetto,Margot Paulino, Rodrigo Segura, Jaime Pizarro, Brenda Vera, Mercedes González, Ana M. Zarate, Cristian O. Salas. (2020). 353:1900213 Archiv der Pharmazie IF= 5,1 https://doi.org/10.1002/ardp.201900213
  16. Pizarro, J., Segura, R., Tapia, D., Navarro, F., Fuenzalida, F., & Aguirre, M. J. (2020) Inexpensive and green electrochemical sensor for the determination of Cd(II) and Pb(II) by square wave anodic stripping voltammetry in bivalve mollusks 321:126682 Food Chemistry IF= 6,306 (2019)
  17. Paulina Meza, Silvana Vaccaro, Judith Faundes, Rodrigo Segura, Juana Andrea Ibacache. (2020) Short and Improved Synthesis of Cytotoxic Homodimers with an Isoquinoline Structure. 71:58-64 Revista de Chimie  IF= 1,755 (2019) https://doi.org/10.37358/RC.20.5.8113
  18. Claudia Núñez, Juan José Triviño, Rodrigo Segura,Verónica Arancibia (2020) Development of a fast and sensitive method for determination of As(III) at trace levels in urine by differential pulse anodic voltammetry using a simple graphene screen-printed electrode. 159:105393 Microchemical Journal IF= 3,594 https://doi.org/10.1016/j.microc.2020.105393
  19. Daniela Espinoza, Alberto González, Jaime Pizarro, Rodrigo Segura, Daniel Laporte, Fernanda Rodríguez-Rojas, Claudio A. Sáez  and Alejandra Moenne (2021) Ulva compressa from Copper-Polluted Sites Exhibits Intracellular Copper Accumulation, Increased Expression of Metallothioneins and Copper-Containing Nanoparticles in Chloroplasts. 19:10531  International Journal of Molecular Sciences. https://doi.org/10.3390/ijms221910531 IF= 5,923
  20. Claudia Núñez1,*, Rodrigo Segura1 , Verónica Arancibia (2021) Development of an amperometric sensor based on the synergistic action between alginic acid and nPEDOT on a gold nanoparticle-modified screen–printed carbon electrode for As(III) determination in natural water samples. International Journal of Electrochemical Science IF=1,573 doi:10.20964/2021.12.31
  21. Fabiana Liendo, Amaya Paz de la Vega, Maria Jesus Aguirre, Fernando Godoy, Angel A. Martí, Erick Flores, Jaime Pizarro, Rodrigo Segura. (2022) A simple graphene modified electrode for the determination of antimony (III) in edible plants and beverage 159:105393 Food Chemistry IF= 6,306
  22. Maialen Aldabaldetrecu, Mick Parra, Sarita Soto-Aguilera, Pablo Arce, Amaya Paz de la Vega Quiroz, Rodrigo Segura, Mario Tello, Juan Guerrero*, Brenda Modak * (2022) Protective Effect of [Cu(NN1)2](ClO4) Complex in Rainbow Trout Challenged against Flavobacterium psychrophilum 10:2296  Microorganisms iF=4.926. https://doi.org/10.3390/microorganisms10112296 
  23. Freddy Navarro, Rodrigo Segura, Fernando Godoy,Angel A. Martí, Carolina Mascayano, Maria J. Aguirre ,Erick Flores, Jaime Pizarro (2023) Fast and Simple Preparation of a Sensor Based on Electrochemically Reduced Graphene Oxide (rGO) for the Determination of Zopiclone in Pharmaceutical Dosage by Square Wave Adsorptive Stripping Voltammetry (SWAdSV) 35:2200357 Electroanalysis https://doi.org/10.1002/elan.202200357
  24. Bryan Pichún, Claudia Núñez, Verónica Arancibia, Angel A. Martí, María J. Aguirre, Jaime Pizarro,·Rodrigo Segura, Erick Flores. (2023) Enhanced voltammetric sensing platform based on gold nanorods and electrochemically reduced graphene oxide for As(III) determination in seafood samples. Journal of Applied Electrochemistry https://doi.org/10.1007/s10800-023-02026-3
  25. Scarlett Aguilera, Erick Flores, Rodrigo Segura, Herna Barrientos, Paulina Márquez, Camilo García, Felipe Matamala-Troncos, Jaime Pizarro, MaríaAguirre. (2023) A simple electroanalytical methodology for determination of zaleplon by adsorptive stripping voltammetry in oral fluids. 193:109256 Microchemical Journal
  26. Salinas, Arturo;Triviño, Juan José;Alvarez-Lueje, Alejandro;Pizarro, Isabel;Segura, Rodrigo;Arancibia, Verónica. (2024) Anodic stripping voltammetry of arsenic determination with edible mushroom-nafion-modified glassy carbon electrode. 277:126391 Talanta   https://doi.org/10.1016/j.talanta.2024.126391
  27. Penagos-Llanos, Johisner;Segura, Rodrigo;de la Vega, Amaya Paz;Pichun, Bryan;Liendo, Fabiana;Riesco, Fernando;Nagles, Edgar. (2024) Electrochemical Determination of Uric Acid Using a Nanocomposite Electrode with Molybdenum Disulfide/Multiwalled Carbon Nanotubes (MoS@MWCNT). Nanomaterials (Basel, Switzerland) 10.3390/nano14110958
  28. Stephanie Romero, Alberto González, Hector Osorio, Rodrigo Segura, Alejandra Moenne *. (2024) Copper is accumulated as copper sulfide particles, and not bound to glutathione, phytochelatins or metallothioneins, in the marine alga Ulva compressa (Chlorophyta). International Journal of Molecular Sciences
  29. Fernando Riesco, Gloria A. Cosco-Salguero, Edgar Nagles, Johisner Penagos-Llanos, Rodrigo Segura, John Hurtado. (2025) Edgar Nagles.  193:109256 Electroanalysis.
Investigaciones : 
  • FONDECYT 1230628 (2023-2027): “Development of electroanalytical sensors based on screen-printed electrodes modified with nanomaterials for the determination of metal ions”. Investigador Responsable
  • FONDECYT 1211637 (2023-2027): “Design and application of multichannel chemosensors of environmentally relevant analytes; n´n and NHC transition metal complexes as the building blocks of sensitive and selective platforms. Coinvestigador.
  • 5392202SS-ACDicyt (2022). Development of analytical methodologies for the determination of heavy metal ions, with electrodes modified with nanomaterials, immobilized from diazonium salts or drop casting applied to different matrices. Investigador Responsable
  • Proyecto CORFO CODIGO 21SNM-15668888. (2021) Sensor electroquímico para la determinación de Li en salmueras productivas. Investigador 
  • FONDECYT 1211637 (2021-2023): “Development of electroanalytical methodologies for redox speciation of metal(loids) (As, Cr, Se) and chromatographic methodologies for the determination of organometallics species (As, Hg, Sn) in different matrices.” Coinvestigador.
  • Proyecto Innovación Docente (PID 072-2017). Armonización micro curricular de la Carrera de Química y Farmacia. Investigador Responsable.
  • FONDECYT 1191130 (2019-2023):  Organometallic complexes linked to macrocycle groups by a chelating bridging ligand, as potential water-soluble or immobilized sensors for the detection of metal ions. Coinvestigador.
  • FONDECYT 1180804 (2018-2021): “development of analytical methodology based on electrochemical sensors with carbon and/or gold nanomaterials for the determination of metal ions”. Investigador Responsable.
  • PROYECTO INNOVACIÓN DOCENTE (PID 072-2017). Armonización micro curricular de la carrera de química y farmacia. Investigador Responsable.
  • PROYECTO INNOVACIÓN DOCENTE (PID 091-2016). “Diseño e implementación de prácticas de laboratorio de las asignaturas de tecnología farmacéutica I y II para la carrera de química y farmacia. Coinvestigador Responsable
  • PROYECTO INNOVACIÓN DOCENTE (PID 008-2015). Diagnóstico del diseño curricular de la carrera de química y farmaciaInvestigador Responsable
  • FONDECYT 11402206 (2014-2017): “Chemically modified electrodes based on macrocyclic compounds type crown ethers for electroanalytical determination of trace metal in real samples”. Investigador Responsable.
  • DICYT 021242SS (2012-2014): “Development of analytical methods for the determination of trace metals in natural water used electrochemical technical with modified bismuth film electrodes. Investigador Responsable.
  • FONDECYT 11070046 (2012 - 2015) “Syntheses and reactivity of crown ether and mixed-aza-macrocyles cyclopentadienyl rhenium complexes as a potenctial electrochemical and optical sensors”. Co-Investigador.
  • FONDECYT 11070046 (2007-2010) “Optimization of methodology of stripping voltammetry for the determination of trace metals in environmental samples using a bismuth film electrode” Investigador Responsable.
  • FONDECYT 3060070. (2006-2007) “caracterización y aplicación analítica del electrodo de bismuto”. Laboratorio de Química Analítica, Facultad de Ciencias. Universidad de Chile. Investigador Responsable
  • Beca Posdoctoral. (2005-2006) Ingeniería Hidráulica y Ambienta. Pontificia Universidad Católica de Chile
  • Beca de Término de Tesis Doctoral (2004) CONICYT.
  • Beca para estudiantes de Doctorado (2002-2004) CONICYT
  • Beca de intercambio estudiantil (2002) Intercampus, Para estadías de Investigación AGCI , España.
  • FONDECYT 2010094. “Aplicación de técnicas espectroscópicas, electroquímicas y de separación (GC. HPLC, Centrifugación, Sfe,Spe,Etc.) En La Especiación De Metales Pesados En El Rio Mapocho”

 

Otras actividades relevantes: 

Número de tesis dirigidas en los últimos 10 años:

 

Magister:                   Dirigidas:        1--                   En desarrollo:             --

Doctorado:                Dirigidas:                                En desarrollo:             1

 

  • Miembro del Comité Académico Nacional CAN (Olimpiadas Chilenas de Química). 2011- a la fecha.
  • Comité Académico de las Olimpiadas de Conocimiento. Universidad de Santiago de Chile. 2012- a la fecha.
  • Comité de Carrera. Química y Farmacia. Facultad de Química y Biología. Universidad de Santiago de Chile. 2012 a la fecha
  • Comité de Carrera Técnico Universitario en Análisis Químico y Físico. Facultad de Química y Biología. Universidad de Santiago de Chile.  2010 a la fecha.
  • Comité editorial revistas científicas

 

  • Referee de revistas internacionales
  1. Journal of Electroanalytical Chemistry
  2. Journal of Colloid & Interface Science:
  3. African Journal of Environmental Science and Technology.
  4. Journal of Hazardous Materials
  5. International Journal of Environmental Analytical Chemistry.
  6. Journal of Oceanology and Limnology
  7. International Journal of ElectrochemistryModern
  8. Journal Of The Chilean Chemical

              

  • Revisor de proyectos
  • Par evaluador de Postgrado
  • Comité de sociedades científicas
  • Sociedad Chilena de Química,  División Química Analítica y Ambiental.
  • Participación en claustro de doctorados
  • Doctorado en Química Universidad de Santiago. (ADJUNTO) 2011-