Ortiz Cisternas Fernando Andrés

Email: 
fernando.ortiz.c@usach.cl
Sitio web: 
Myelin Lab
Abstract: 
Our research  aims to understand the mechanisms underlying the formation and repair of myelin, a special membrane present in our nervous system allowing neurons for fast conduction and proper communication. In particular, we are interested in how oligodendrocytes - the myelin-forming cells of the central nervous system-, interact with other glial cells and neurons in the brain in health and disease.
Línea(s) de investigación: 
Neuroinflamación
Regeneración
Interacción glia-glia y glia-neurona
Mecanismos celulares en la esclerosis múltiple
Grados académicos /educación: 
2011 Ph.D. Ciencias Fisiológicas, Facultad de Ciencias Biológicas, P. Universidad Católica de Chile.
2007 Mg. Ciencias Fisiológicas, Facultad de Ciencias Biológicas, P. Universidad Católica de Chile.
2004 Licenciado en Ciencias, mención Fisiología, Facultad de Ciencias, Universidad de Chile.
Publicaciones: 
  • Guevara C, Varas R, Angulo MC, Ortiz FC (2023) Electrophysiological recordings of oligodendroglia in adult mouse brain slices. Methods in Molecular Biology, in New Technologies for Glutamate Interaction: Neurons and Glia, Springer Nature, In Press
  • De la Paz JF, Zambrano NO, Ortiz FC, Llanos-Rivera A. (2023) A New Bioassay for the Detection of Paralytic and Amnesic Biotoxins Based on Motor Behavior Impairments of Zebrafish Larvae. Int J Mol Sci. 24(8):7466. doi: 10.3390/ijms24087466.
  • Allendes FJ, Díaz HS, Ortiz FC, Marcus NJ, Quintanilla R, Inestrosa NC, Del Rio R. (2023) Cardiovascular and autonomic dysfunction in long-COVID syndrome and the potential role of non-invasive therapeutic strategies on cardiovascular outcomes. Front Med 2023 Jan 19;9:1095249. doi: 10.3389/fmed.2022.1095249.
  • Maldonado PP, Guevara C, Olesen MA, Orellana JA, Quintanilla RA, Ortiz FC “Neurodegeneration in Multiple Sclerosis: The Role of Nrf2-Dependent Pathways” (2022) Antioxidants 11(6):1146. doi:10.3390/antiox11061146.
  • Toledo C, Andrade DC, Diaz-Jara E, Ortolani D, Bernal-Santander I, Schwarz KG, Ortiz FC, Marcus NJ, Oliveira LM, Takakura AC, Moreira TS, Del Rio R. (2022) Cardiorespiratory alterations following intermittent photostimulation of RVLM C1 neurons: Implications for long-term blood pressure, breathing and sleep regulation in freely moving rats. Acta Physiol 236(3):e13864. doi: 10.1111/apha.13864.
  • Díaz HS, Ríos-Gallardo A, Ortolani D, Díaz-Jara E, Flores MJ, Vera I, Monasterio A,  Ortiz FC, Brossard N, Osorio F, Del Río R (2022) “Lipid-Encapsuled Grape Tannins Prevent Oxidative-Stress-Induced Neuronal Cell Death, Intracellular ROS Accumulation and Inflammation” Antioxidants 11:1928. https://doi.org/10.3390/antiox11101928
  • Olivares MJ, Toledo C, Ortolani D, Ortiz FC, Díaz HS, Iturriaga R, Del Río R (2022) “Sleep dysregulation in sympathetic-mediated diseases: implications for disease progression” Sleep. zsac166. doi: 10.1093/sleep/zsac166
  • Toledo C, Ortolani D, Ortiz FC, Marcus NJ, Del Rio R (2022) “Potential Role of the Retrotrapezoid Nucleus in Mediating Cardio-Respiratory Dysfunction in Heart Failure With Preserved Ejection Fraction” Front Physiol.13:863963. doi: 10.3389/fphys.2022.863963.
  • Schwarz KG, Pereyra KV, Toledo C, Andrade DC, Díaz HS, Díaz-Jara E, Ortolani D, Rios-Gallardo A, Arias P, Las Heras A, Vera I, Ortiz FC, Inestrosa NC, Vio CP, Del Rio R (2021) “Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure” Biol Res. 54(1):43. doi: 10.1186/s40659-021-00365-z.
  • Andrade DC, Melipillan C, Toledo C, Rios-Gallardo A, Marcus NJ, Ortiz FC, Martinez G, Muñoz Venturelli P, Del Rio R (2021) “Heart rate and cardiac autonomic responses to concomitant deep breathing, hand grip exercise, and circulatory occlusion in healthy young adult men and women” Biol Res. 54(1):32. doi: 10.1186/s40659-021-00355-1.
  • Díaz-Jara E, Díaz HS, Rios-Gallardo A, Ortolani D, Andrade DC, Toledo C, Pereyra KV, Schwarz K, Ramirez G, Ortiz FC, Andía ME, Del Rio R (2021) “Exercise training reduces brainstem oxidative stress and restores normal breathing function in heart failure” Free Radic Biol Med. 172:470-481. doi:10.1016/j.freeradbiomed.2021.06.032.
  • Andrade DC, Díaz-Jara E, Toledo C, Schwarz KG, Pereyra KV, Díaz HS, Marcus NJ, Ortiz FC, Ríos-Gallardo AP, Ortolani D, Del Rio R (2021) "Exercise intolerance in volume overload heart failure is associated with low carotid body mediated chemoreflex drive” Sci Rep 11(1):14458. doi: 10.1038/s41598-02193791-8.
  • Guevara C, Ortiz FC (2021) “Glial-derived transforming growth factor β1 (TGF-β1): a key factor in multiple sclerosis neuroinflammation” Neural Regen Res 16(3):510-511. doi: 10.4103/16735374.293147.
  • Pereyra K, Schwarz K, Andrade D, Toledo C, Rios-Gallardo A, Díaz-Jara E, Bastías S, Ortiz FC, Ortolani D, Del Rio R, (2021) “Paraquat herbicide diminishes chemoreflex sensitivity, induces cardiac autonomic imbalance and impair cardiac function in rats”. Am J Physiol Heart Circ Physiol 320:H1498-H1509. doi: 10.1152/ajpheart.00710.2020
  • Habermacher C, Manot-Saillet B , Ortolani D, Ortiz FC, Angulo MC (2020) “Optogenetics to interrogate neuron-glia interactions in pups and adults” Methods in Molecular Biology. 2191:135-149. doi:10.1007/978-1-0716-0830-2_9.
  • Sáez JC, Vargas AA, Hernández DE, Ortiz FC, Giaume C, Orellana JA. (2020) “Permeation of Molecules through Astroglial Connexin 43 Hemichannels Is Modulated by Cytokines with Parameters Depending on the Permeant Species” Int J Mol Sci 21(11):E3970. doi: 10.3390/ijms21113970 
  • Varas R, Ortiz FC (2020) “Neuroinflammation in demyelinating diseases: oxidative stress as a modulator of glial cross-talk” Curr Pharm Des. 25:4755-4762. doi:10.2174/1381612825666191216125725
  • Ortiz FC, Puebla C (2020) “Pannexin 1-based channels activity as a novel regulator of multiple sclerosis progression” Neural Regen Res 15(1):65-66. doi:10.4103/1673-5374.264450
  • Baraban M, Retamal MA, Ortiz FC (2019) Editorial: Physiology of Myelin Forming Cells, from Myelination to Neural Modulators. Front Cell Neurosci 13:475 doi: 10.3389/fncel.2019.00475
  • Ortiz FC, Habermacher C, Graciarena M, Houry P-Y, Nishiyama A, Nait-Oumesmar B, Angulo MC (2019)  “Neuronal  activity  in  vivo  enhances  functional  myelin  repair”  JCI  insight. JCI insight. 21: 5 pii:123434.
  • Vejar S, Oyarzún JE, Retamal MA*, Ortiz FC*, Orellana JA* (2019) “Connexin and pannexin-based channels in oligodendrocytes: implications in brain health and disease” Front Cell Neurosci 13:3 doi: 10.3389/fncel.2019.00003 *co-corresponding authors.
  • Ortolani D, Manot-Saillet B, Orduz D, Ortiz FC* and Angulo MC* (2018) In vivo Optogenetic Approach to Study Neuron-Oligodendroglia Interactions in Mouse Pups. Front. Cell. Neurosci. 12:477. doi: 10.3389/fncel.2018.00477 *co-corresponding authors.
  • Pulgar-Sepúlveda R, Varas R, Iturriaga R,Del Rio R*, Ortiz FC* (2018) “Carotid Body Type-I Cells Under Chronic Sustained Hypoxia: Focus on Metabolism and Membrane Excitability” Front. Physiol. 9:1282 *co-corresponding authors
Premios y Honores: 
  • 2015 Award for the Best Oral Communication, Annual Meeting on Multiple Sclerosis, ARSEP Foundation, Paris.
  • 2015-2016 French Multiple Sclerosis Research Society (ARSEP) Research Award fellowship
  • 2014 Award for the Best Poster Presentation, Annual Meeting on Multiple Sclerosis, ARSEP Foundation, Paris.
  • 2013-2015 Medical Research Foundation (FRM, France) Research Award fellowship
  • 2009 Graduate Assistantship, CONICYT, National Fund for Scientific and Technological Development
  • 2008 Graduate Assistantship, VRIP, P. Universidad Católica de Chile
  • 2006-2010 Graduate Fellowship, CONICYT, National Fund for Scientific and Technological Development
Investigaciones : 

Los principales proyectos de investigación de nuestro laboratorio son:

  • Rol de TGFb-1 liberado por los astrocitos en la progresión de la desmielinización y remielinización en modelos murinos de esclerosis múltiple
  • Determinación de la respuesta antioxidante mediada por la activación de la vía Nrf2 en lesiones desmielinizadas y su relación con la regeneración de mielina
  • Estudio del efecto de la estimulación vagal sobre la neuroinflamación y la inflamación periférica
  • Estudio de la función y expresión de los canales de Panexina-1 durante la progresión de la desmielinización y remielinización en modelos murinos de esclerosis múltiple
  • Caracterización electrofisiológica de la comunicación glia-neurona en tractos de sustancia blanca del sistema nervioso central
Proyectos: 
  • 2021-2025 Chilean National Fund for Scientific and Technological Development (FONDECYT) Regular, Research Grant #1210940, Astrocytic cytokine signaling in multiple sclerosis:implications in disease progression. Principal Investigator.
  • 2021-2022 VRIP  Universidad  Autónoma  de  Chile  DIUA210-2021.  Vagal nerve stimulation: a new approach to treat MS, Research Grant, Co-Investigator (P.I. Dr. Rodrigo Varas).
  • 2019-2020 VRIP  Universidad  Autónoma  de  Chile  DIUA166-2019.  Role of astrocytic TGF-β1 on remyelination. Principal Investigator.
  • 2019-2021 ECOS-CONICYT. Research Grant, Principal Investigator (international partner: Dr. Maria Cecilia Angulo, Center of Psychiatry and Neurosciences. INSERM U894, Paris, France)
  • 2018-2021 NeurATRIS  (“translational  research  infrastructure  for  innovative  therapies  in Neuroscience-EU/France”)   project.   Research   Grant,   Principal   Investigator (international partner: Dr. Carole Escartin, CEA, MIRCen, Fontenay-aux-roses, France)
  • 2018-2019 Supporting Fund for the Formation of International networks for young researchers “REDES-CONICYT”,   FONDECYT  PCI   REDI170037,  Research   Grant,   Principal Investigator.
  • 2018-2019 VRIP Universidad  Autónoma  de  Chile  DIUA127-2018.  Effect  of  astrocyte photoactivation on oligodendrocyte differentiation in demyelinated lesions, Research Grant, Co-Investigator (P.I. Dr. Rodrigo Varas).
  • 2017-2019 Chilean National Fund for Scientific and Technological Development (FONDECYT) Iniciación, Research Grant #11160616, Role of astrocytes in the remyelination of the corpus callosum in a model of MS lesions. Principal Investigator.
Otras actividades relevantes: 
Dirección de tesis:
  • 2022-2023    Dirección Tesis de Magister. Magíster en Neurociencia, Universidad Autónoma de Chile. Estudiante: Viviana Rios. Tesis: Efectos de la terapia fonoaudiológica sobre las habilidades cognitivas-comunicativas y la progresión de las lesiones del tejido nervioso en personas con esclerosis múltiple secundaria progresiva: reporte de un caso clínico  (graduada)
  • 2022- Dirección tesis de doctorado. PhD program on Biomedical Sciences, Universidad Autónoma de Chile. Estudiante: Sebastián Vejar. Tesis: Estimulación vagal en un modelo murino de esclerosis múltiple: efectos sobre neuroinflamación, desmielinización y daño periférico  (en progreso)
  • 2022-    Co-dirección tesis de doctorado. PhD program on Physiology, P. Universidad Católica de Chile. Estudiante: Katherin Pereyra. Tesis: “Contribution of the Inflammasome to Carotid Body Potentiation in Heart Failure with Preserved Ejection Fraction: Role in Disease Progression” (en progreso)
  • 2021-   Dirección tesis de doctorado.  PhD program on Biomedical Sciences, Universidad Autónoma de Chile. Estudiante: Coram Guevara. Tesis: Participación de la vía Nrf2 en el daño mitocondrial y neuroinflamación en lesiones desmielinizantes inducidas por cuprizona  (en progreso)
  • 2022-2023  Dirección Tesis de Magister. Magíster en Neurociencia, Universidad Autónoma de Chile. Estudiante: Francisco Zamora. Tesis: Efecto de la musicoterapia sobre la función celular en el sistema nervioso central: una revisión sistemática (in progress)
  • 2021- 2023 Dirección Tesis de pregrado, carrera Bioquímica. Pontificia Universidad Católica de Valparaíso. Estudiante: Sinay Vicencio.  Tesis: Caracterización de las vías colinérgicas del troncoencéfalo en un modelo murino de Esclerosis Múltiple
  • 2019-2021  Pasantía experimental. Escuela de Medicina, Universidad Autónoma de Chile. Estudiante: Andres Munoz. Tema: Setting a new model of multiple sclerosis: demyelinated lesions in cerebellum, Funded by ‘UA-Scientific Initiation Fellowship’.
  • 2018            Pasantía experimental.   María García- Blanes Martínez, Bioquímica, Universidad Autónoma de Madrid. Tema: Immunohistochemistry and confocal imaging of glial cells in demyelinated lesions.
  • 2018            Práctica profesional, carrera Bioquímica. Pontificia Universidad Católica de Valparaíso. Estudiante: Sebastian Vejar. Tema:  Setting  a  station  for  electrophysiological  recordings, electrophysiological characterization of glial cells.
  • 2017-2018  Pasantía experimental. Escuela de Medicina, Universidad Autónoma de Chile. Estudiante: Benjamin Suarez Camus. Tema:  Immunohistochemistry  and electrophysiological characterization of demyelinated lesions, Funded by ‘UA-Scientific Initiation Fellowship’.
  • 2014-2015   Co-dirección Tesis de Magister. Master Biologie et Santé-signalisation cellulaire-neuroscience, Paris Sud University. Student: Pierre-Yves Houry. Thesis: Role of the Neuronal Activity on the  oligodendroglia  during  the  remyelination  of  corpus  callosum.  Paris  Descartes University.
  • 2013-2014  Co-dirección Tesis de Magister.  Master II recherche de science et technologie Mention Biologie intégrative  et  physiologie,  Spécialité  neurosciences.  Student:  Nour  Barça.  Thesis: Expression of NMDA receptor-mediated currents of oligodendrocyte precursor cells during early postnatal development and following demyelination of the mouse corpus callosum. Paris Descartes University.

 

Actividades de Divulgación científica. Un eje central de nuestro laboratorio es la diseminación del conocimiento científico a través de diversos medios de divulgación, entre los que se cuentan los siguientes: 
  • Creacion de material audiovisual para la doivulgacion cientifica asociado al director de cine y animador Samuel Restucci. Actualmente desarrollamos animcaion clasica 2D y escenarios de realidad virtual  

https://www.youtube.com/watch?v=0nV_Ck7k-8U&feature=emb_title

https://www.instagram.com/tv/CfEvJzQMQ8C/?igshid=MzRlODBiNWFlZA%3D%3D 



Creacion de libros de cuentos para público adolescente con diversas temáticas científicas. 

https://ciencias.uautonoma.cl/relatos-de-tu-conciencia

Pasantias en nuestro laboratorio.Hemos creado un programa de pasantías de corta duración para estudiantes de enseñanza media del area metropolitana

https://myelin-lab.cl/divulgacion/



Creador de contenido de la “Fundación Chile Hace Ciencia”

https://chilehaceciencia.wordpress.com/contenidos/blog/pongamosle-forrito/

https://chilehaceciencia.wordpress.com/contenidos/blog/comunes-y-corrientes/

https://chilehaceciencia.wordpress.com/contenidos/blog/nobel-de-medicina-2014-un-gps-en-las-profundidades-del-cerebro-1/

 

 

Congresos: 
  • 2023 Vejar S, Pulgar-Sepulveda R, C. Guevara, S. Vicencio, R. Del Rio, R. Varas, Ortiz FC; Vagal Nerve Stimulation reduces neuroinflammation of demyelinated lesions in a murine model of Multiple Sclerosis, poster session, Germany, XVI European Meeting on Glial Cells in Health and Disease, Berlin
  • 2023 Guevara C, Vicencio Orellana S , S. Vejar Contuliano, F. Villavicencio, M. Olsen, Quintanilla R, Ortiz FC; Is TGFβ-1-signaling required for Nrf2-antioxidant pathway activation in a murine model of multiple sclerosis? poster session, Germany, XVI European Meeting on Glial Cells in Health and Disease, Berlin
  • 2023 Ortolani D, Ortiz FC, Del Rio R; Chronic inhibition of voltage-gated potassium channels by angiotensin II in catecholaminergic neurons require ROS generation through an NADPH-oxidase independent pathway, poster session, Puerto Rico, 34th International Symposium of American Autonomic Society (AAS), Grand Rio Mar
  • 2023 Vejar S, Villavicencio F, Guevara C, Ortiz FC; Vagal nerve stimulation in Multiple Sclerosis: a non-pharmacological approach to reduce neuroinflammation and disease progression, oral communications session, Chile, XIX Annual meeting of the Chilean Society for Neuroscience, La Serena
  • 2023 Zamora F, Ortiz FC; Does music-based therapy have effects on CNS cellular physiology? : a systematic review, poster session, Chile, XIX Annual meeting of the Chilean Society for Neuroscience, La Serena
  • 2023 Guevara C, Vejar S, Silva-Pizarro I, Villavicencio F,  Olsen M, Ampuero E, Quintanilla R, Ortiz FC; Sexual differences in Nrf2-antioxidant pathway activation in a murine model of multiple sclerosis, poster session, Chile, XIX Annual meeting of the Chilean Society for Neuroscience, La Serena
  • 2023 Rios V, Matus P, Ortiz FC; Effects of speech therapy on RMI-identified demyelinated lesions and cognitive-communicative skills in multiple sclerosis: a case report, poster session, Chile, XIX Annual meeting of the Chilean Society for Neuroscience, La Serena
  • 2023 Escobar M, Polit A, Vejar S, Pulgar-Sepúlveda R, Vicencio S, Ortiz FC; A murine model of sensorineural hearing loss in multiple sclerosis, poster session, Chile, XIX Annual meeting of the Chilean Society for Neuroscience, La Serena
  • 2023 Pulgar-Sepúlveda R, Ortiz FC, Eugenin J; Demyelination of PreBötC reduces the ventilatory response induced by hypercapnia, poster session, Chile, XIX Annual meeting of the Chilean Society for Neuroscience, La Serena
  • 2023 Silva-Pizarro I, Pulgar-Sepúlveda R, Vejar S, Puebla C, Ortiz FC; Effect of Probenecid on pre-clinical and histological signs in Multiple Sclerosis mice models, poster session, Chile, XIX Annual meeting of the Chilean Society for Neuroscience, La Serena
  • 2023 Polit A, Nuñez A, Ortiz FC; Lesiones desmielinizantes en el cerebelo: un modelo preclínico para el estudio de la esclerosis multiple, poster session, Chile, Annual meeting Academia de cirugia, urgencias y trauma de estudiantes de medicina, online meeting
  • 2023 Ortolani D, Ortiz FC, Del Rio R; Angiotensin II-induced inhibition of delayed rectifier potassium currents in sympathetic catecholaminergic neurons requires endoplasmic reticulum, poster session, Brazil, 5th Neural Control of Breathing Meeting, São Paulo
  • 2022 Ortolani D, Ortiz FC, Del Rio R;  Chronic angiotensin II inhibits delayed rectifier potassium currents in differentiated pre-sympathetic catecholaminergic neurons, poster session,Chile, XXXVII Reunión Anual Sociedad Chilena de Ciencias Fisiológicas, La Serena
  • 2022 Guevara C, Vejar S, Villavicencio F, Olsen M, Reyes J, Amador C, Quintanilla R, Ortiz FC; Contribution of the Nrf2 antioxidant pathway to the neuroinflammation in a cuprizone model of multiple sclerosis, poster session, Chile, Annual meeting of the Chilean Society for Neuroscience, Pucón
  • 2022 Pulgar- Sepúlveda R, Eugenin Leon J, Ortiz FC; Myelin damage in the PrebotC: effects on the respiratory rhythm, poster session, Chile, Annual meeting of the Chilean Society for Neuroscience, Pucón
  • 2022 Vejar S, Muñoz A, Guevara C, Vicencio S, Varas R, Ortiz FC; Vagal nerve stimulation as a potential treatment for MS: insights from a preclinical murine model, poster session, Chile, Annual meeting of the Chilean Society for Neuroscience, Pucón
  • 2022 Vicencio S, Vejar S, Guevara C, Reyes J, Amador C, Varas R, Ortiz FC; Characterization of brainstem cholinergic pathways in the demyelinating stages of a murine model of multiple sclerosis, poster session, Chile, Annual meeting of the Chilean Society for Neuroscience, Pucón 
  • 2022 Vicencio S, Vejar S, Guevara C, Reyes J, Varas R, Ortiz FC; Caracterización de las vías colinérgicas del troncoencéfalo en las etapas desmielinizantes de un modelo murino de esclerosis múltiple, poster session, Chile, Prisma meeting 2022 ANEB, Valdivia 
  • 2022 Vejar S, Pulgar- Sepúlveda R, Guevara C, Vicencio S, Del Rio R, Varas R, Ortiz FC; Impact of Vagal Nerve Stimulation on the progression of demyelinated lesions in a murine model of Multiple sclerosis, poster session, France, Federation of European neuroscience societies (FENS) forum 2022, Paris
  • 2021 Muñoz A, Vejar S, Varas R, Ortiz FC; Efecto de la estimulación vagal sobre la remielinización en un modelo murino de EM, poster session, Chile, II Jornada de jóvenes investigadores en Salud, Universidad de O´Higgins, Rancagua
  • 2021 Pulgar-Sepulveda R, Vejar S, Puebla C, Ortiz FC; Rol de los canals formados por panexina-1 en la progression de lesiones desmielinizantes, poster session, Chile, II Jornada de jóvenes investigadores en Salud, Universidad de O´Higgins Rancagua
  • 2019 Guevara C, Muñoz A ; Nuñez A, ; Pulgar-Sepúlveda R, Cea LA, Andrade D, Toledo C, Del Rio R, Ortiz FC; Focal Demyelination in the Cerebellum: a Preclinical Model for the Study of Multiple Sclerosis, poster session, Chile, XV Annual meeting of the Chilean society for Neuroscience, La Serena.
  • 2019 Pulgar-Sepúlveda R., Carrillo-de Sauvage MA, Vejar S, Flament J, Escartin C, Ortiz FC; Dissecting the Contribution of Reactive Astrocytes to Myelin Repair, poster session, Chile, XV Annual meeting of the Chilean society for Neuroscience, La Serena
  • 2019 Vejar S, Habermacher C, Guevara C, Pulgar-Sepúlveda R, Angulo MC, Varas R, Ortiz FC; Effect of Astrocytes Photo-activation on Remyelination in Freely Moving Mice, poster session, Chile  XV Annual meeting of the Chilean society for Neuroscience, La Serena.
  • 2019 Carrillo-de Sauvage MA, Pulgar-Sepúlveda R., Vejar S, Flament J, Escartin C, Ortiz FC; Contribution of Reactive Astrocytes to Myelin Repair, poster session, Portugal, XIV European Meeting on Glial Cells in Health and Disease, Porto.
  • 2019 Pulgar-Sepúlveda R., Carrillo-de Sauvage MA, Vejar S, Flament J, Escartin C, Ortiz FC; Exploring the Contribution of Reactive Astrocytes to Myelin Repair, poster  session, France, Annual  meeting  of  the  French society  for Neuroscience (Neurofrance 2019), Montpellier.
  • 2018 Vejar S, Pulgar-Sepúlveda R, Varas R, Ortiz FC; Effect of astrocyte activity on axon-oligodendroglia glutamatergic  transmission,  poster  session,  Chile,  Annual  meeting  of  the  Chilean  society  for Neuroscience, Puerto Varas.
  • 2018 Pulgar-Sepúlveda R, García-Blanes M, Vejar S, Suarez B, Varas R, Ortiz FC; Effects of astrocyte activity on myelin regeneration, poster session, Chile, Annual meeting of the Chilean society for Neuroscience, Puerto Varas.
  • 2018 Gomez G, Avendaño B, Ortiz FC, Puebla C. Alpha–linolenic acid decreases the myogenic differentiation of c2c12 cells, poster session, Chile, Annual meeting of the Chilean society for Neuroscience, Puerto Varas.
  • 2018 Pulgar-Sepúlveda R, Vejar S, Varas R, Ortiz FC; Effects of astrocyte activity on axon-OPC glutamatergic transmission, poster session, France, Annual meeting of the French Club of glial Cells, Paris.
  • 2018 García-Blanes M, Pulgar-Sepúlveda R, Vejar S, Suarez B, Varas R, Ortiz FC; Dissecting astrocyte- activity contribution to myelin repair, poster session, France, Annual meeting of the French Club of glial Cells, Paris.
  • 2018 Habermacher C, Ortiz FC, Houry PY, Graciarena M., Nait-Oumesmar B., Angulo MC; Increased neuronal activity on remyelination, poster session, France, Annual meeting of the French Club of glial Cells, Paris.
  • 2018 Ortolani D, Manot-Saillet B, Ortiz FC, Angulo MC, An in vivo optogenetic approach to study neuron-oligodendroglia interactions in mouse pups, oral session, France, Ion Channel Meeting, Séte.
  • 2018 Ortiz FC, Habermacher C, Houry PY, Graciarena M., Nait-Oumesmar B., Angulo MC; Effect of increased neuronal activity on remyelination in freely moving mice, poster session, USA, Gordon Research Conference on Myelin, Ventura, CA.