Ion channels are membrane proteins involved in ion transport across cellular membranes, controlling and maintaining the voltage gradient across the cell membrane. My research interest is in understanding how the biophysical properties of ion channels in different neuronal compartments can shape the patterns of action potentials and modulate neuronal excitability.
Jerarquía:
Asistente
Grados académicos /educación:
Doctor en Ciencias con mención en Biología Celular, Molecular y Neurociencias, Facultad de Ciencias, Universidad de Chile, Chile, 2005
Licenciado en Ciencias con mención en Biología, Facultad de Ciencias, Universidad de Chile, Chile, 1996
Email:
ana.sandino@usach.cl
Teléfono:
27 181 113
Research
Research is oriented to:
Isolation and detection of virus from fish tissues.
Development of viral diagnosis method, such as: cellular culture, electrophoresis, PCR, etc.
Effect of antiviral compounds on viral replication, in vitro and in vivo assays.
Study of the viral cycle: transcription, replication, translation and morphogenesis, either in cell culture of in vitro system..
Línea(s) de investigación:
Biología molecular y celular
Jerarquía:
Titular
Grados académicos /educación:
Doctor en Ciencias con Mención en Biología, Universidad de Chile, 1990
Bioquímico, Universidad de Chile, 1984
Email:
mario.tello@usach.cl
Non-ribosomal peptides and polyketides are a wide group of Bioactive substance with pharmaceutical properties such as antibiotics, antineoplasic, antiviral, immunomodulators, etc. These compounds are synthesized by big multidomain proteins called Non ribosomal peptide synthetase (NRPS) or Poliketide Synthetase. (PKS), according its ability to synthesize nonribosomal peptides or polyketides, respectively. The aim of this research is to study new PKS or NRPS systems to produce new bioactive compounds. For this purpose we combine bioinformatics, molecular biology, microbiology and cellular biology strategies.
Línea(s) de investigación:
Compuestos Bioactivos sintetizados por PKS o NRPS.
Doctor en Ciencias Biológicas, P. Universidad Católica de Chile, 1983
Bioquímico, Universidad de Chile, 1977
Email:
ruben.vidal@usach.cl
The research of my group is aimed to introduce computational expertise in molecular genetics, conservation genetics, population genetics, phylogeography, comparative genomics, transcriptomics, proteomics and molecular phylogenetics. Our current research is focused on salmonids and includes topics of immunology, discovery and devolopment of SNP plataforms and transcriptomics.
Characterization of the mechanisms of action of plant compounds with antibacterial activities. Bacterial biofilm inhibitors. Application of sulfate reducing bacteria in the treatment of acid mine drainages associated to a wetland system. Bacterial communities studies.
The main interest of my group is the development of methodologies for in vitro plant culture to obtain natural products with biological activity . In addition, we intend the conservation of the germoplasm from native species of Chile.
Línea(s) de investigación:
Biotecnología Vegetal
Jerarquía:
Titular
Grados académicos /educación:
Doctor en Ciencias Biológicas, Universidad de Chile, 1997